竞争性HMGCR抑制剂;a competitive HMGCR inhibitor;普伐他汀是一种竞争性HMGCR(HMG-CoA还原酶)抑制剂,可有效阻断胆固醇合成(K | i |〜1 nM)。普伐他汀具有心脏保护作用,还可以作为免疫调节剂和ras p21异戊二烯化的抑制剂。;Pravastatin is a competitive HMGCR (HMG-CoA reductase) inhibitor that potently blocks cholesterol synthesis (K|i|~1 nM). Pravastatin offers cardioprotection and also acts as an immunomodulator and as an inhibitor of ras p21 isoprenylation.