77. [IF=5.7] Ding Menglei et al."Targeting G-protein-coupled receptors and gut microbiota: Ge-Lian Qi-Shen decoction elevates GLP-1 to combat non-alcoholic fatty liver disease."Chinese Medicine.2026 Dec;21(1):51 76. [IF=5.5] Ruoqing Guan et al."DST-3, a Novel Modified Cryptotanshinone, Protects Against Pulmonary Fibrosis via Inhibiting STAT3/Smad Signaling Pathway and Improves Bioavailability."Pharmaceutics.2025 Oct;17(10):1307 75. [IF=7.9] Ping Huang et al."Purification optimization of tanshinones and their neuroprotection assessment on SH-SY5Y cells injured by oxygen-glucose deprivation/reoxygenation."Results in Engineering.2025 Oct;:107884 74. [IF=8.5] Chaoyue Zheng et al."A magnetic nanoparticles-based ligand fishing method coupled with parallel artificial membrane permeability assay for rapid discovery and analysis of GSNO reductase inhibitors with good membrane permeability from Salvia miltiorrhiza B 73. [IF=8.3] Shufang Li et al."Daphnetin as a novel polyphosphate kinase inhibitor to combat Salmonella infection."PHYTOMEDICINE.2025 Nov;148:157278 72. [IF=3.1] Song Yueyue et al."Compound Danshen decoction identifies its mechanism of antagonizing atherosclerosis by network pharmacology and transcriptomics."NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY.2025 Oct;:1-19 71. [IF=2.5] Zhou Yue et al."Discovery of active compounds in Danshen–Chuanxiong formula for blood–brain barrier protection: a multi-parametric study using an OGD/R-induced spheroid model."Journal of Natural Medicines.2025 Aug;:1-18 70. [IF=2.5] Zhou Yue et al."Discovery of active compounds in Danshen–Chuanxiong formula for blood–brain barrier protection: a multi-parametric study using an OGD/R-induced spheroid model."Journal of Natural Medicines.2025 Aug;:1-18 69. [IF=10.2] Chenjie Xia et al."An efficient brain delivery system co-loaded with multiple components of Salvia miltiorrhiza for synergistic treatment of ischemic stroke."Materials Today Bio.2025 Jul;:102102 68. [IF=3.4] Wang Qiaona et al."Anti-oxidative effect of Salvia miltiorrhiza Bunge fermented with Shiraia bambusicola Henn. against H2O2-induced injury in PC12 cells."BMC Complementary Medicine and Therapies.2025 Dec;25(1):1-13 67. [IF=4] Lijuan Wu et al."Integration of chromatographic fractionation, quantitative 1H-NMR and serially coupled achiral-chiral LC–MS/MS enables multi-components-targeted determination of Salvia miltiorrhiza in an authentic compound-independent manner."JOURNAL OF 66. [IF=4.9] Kewei Zuo et al."Transcriptome- and Metabolome-Based Regulation of Growth, Development, and Bioactive Compounds in Salvia miltiorrhiza (Lamiaceae) Seedlings by Different Phosphorus Levels."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(13):6253 65. [IF=3.8] Liping Zhang et al."Comprehensive characterization of active components in Salvia miltiorrhiza using polarity-partitioned two-dimensional liquid chromatography coupled with mass spectrometry."JOURNAL OF CHROMATOGRAPHY A.2024 Oct;:465424 64. [IF=5.7] Xue-Zhang et al."Discovery of Tetrahydro Tanshinone I as a Naturally Occurring Covalent Pan-Inhibitor Against Gut Microbial Bile Salt Hydrolases."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2024;XXXX(XXX):XXX-XXX 63. [IF=8.3] Ruiyan Zhu et al."Abscisic acid enhances SmAPK1-mediated phosphorylation of SmbZIP4 to positively regulate tanshinone biosynthesis in Salvia miltiorrhiza."NEW PHYTOLOGIST.2024 Nov;: 62. [IF=8.1] Sheng Wang et al."Target-oriented rational design of composite bio-derived solvents for the green extraction of salvianolic acid B and tanshinones from Salvia miltiorrhiza root."SEPARATION AND PURIFICATION TECHNOLOGY.2025 Jun;359:130772 61. [IF=4.9] Yanbing Pan et al."Simultaneous detection of tanshinone I and cryptotanshinone using a carbon fiber microelectrode based on gold–palladium composite network."MICROCHEMICAL JOURNAL.2025 Mar;:113378 60. [IF=6.7] Mingzhu Qi et al."Qingxin Jieyu Granule alleviates myocardial infarction through inhibiting neutrophil extracellular traps via activating ANXA1/FPR2 axis."PHYTOMEDICINE.2024 Dec;135:156147 59. [IF=8.7] Zhe Li et al."Illuminating the fight against breast cancer: Preparation and visualized photothermal therapy of hyaluronic acid coated ZIF-8 loading with indocyanine green and cryptotanshinone for triple-negative breast cancer."Materials Today Bio.2024 Oct 58. [IF=6.2] Ying Ren et al."Effect of CeO2, TiO2 and SiO2 nanoparticles on the growth and quality of model medicinal plant Salvia miltiorrhiza by acting on soil microenvironment."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Jul;280:116552 57. [IF=4.8] Qingquan Li et al."Identification of Senkyunolide I as a novel modulator of hepatic steatosis and PPARα signaling in zebrafish and hamster models."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;336:118743 56. [IF=4.8] Zhengchao Ji et al."Holistic quality assessment and monitoring of YiXinShu capsule based on three-dimensional fingerprints combined with quantitative analysis, antioxidant activity and chemometrics."JOURNAL OF ETHNOPHARMACOLOGY.2024 Dec;335:118630 55. [IF=0.8] Cao Yezhi et al."Cryptotanshinone Inhibits the Proliferation of 5-Fluorouracil-Resistant Gastric Cancer SGC-7901/5-FU Cells Via the JAK2/STAT3 Pathway."PHARMACEUTICAL CHEMISTRY JOURNAL.2024 Jun;:1-10 54. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal 53. [IF=3.1] Miao Wang et al."Tanshinone IIA, originated from Salvia miltiorrhiza, activated EPO/EPOR-JAK2-STAT5 pathway in rat blood deficiency therapy."SOUTH AFRICAN JOURNAL OF BOTANY".2024 Jul;170:105 52. [IF=0.7] Shaomei Lin et al."Effect of Cryptotanshinone on BDNF/TrkB Pathway in Hippocampus of Chronic Stress-induced Depression Rats."Pharmacognosy Magazine.10.1177/09731296241236034 51. [IF=9.8] Ying Ren et al."Response of antioxidant activity, active constituent and rhizosphere microorganisms of Salvia miltiorrhiza to combined application of microbial inoculant, microalgae and biochar under Cu stress."SCIENCE OF THE TOTAL ENVIRONMENT".2024 May;9 50. [IF=1.1] Ji-Yong FU et al."Simultaneous determination of 19 constituents in the Jian-Nao-Ning mixture using high-performance liquid chromatography-tandem mass spectrometry."Separation Science Plus".2024 Feb;:2300222 49. [IF=5.4] Yingkun Sheng et al."Dan-shen Yin promotes bile acid metabolism and excretion to prevent atherosclerosis via activating FXR/BSEP signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118209 48. [IF=3.8] Ying Zhang et al."Elucidating the distinctive regulatory effects and mechanisms of active compounds in Salvia miltiorrhiza Bunge via network pharmacology: Unveiling their roles in the modulation of platelet activation and thrombus formation."TOXICOLOGY AN 47. [IF=4.7] Xu Zhang et al."Rhein: A potent immunomodulator empowering largemouth bass against MSRV infection."FISH & SHELLFISH IMMUNOLOGY.2024 Jan;144:109284 46. [IF=5.4] Yi-Chao Liu et al."Mechanism of cryptotanshinone to improve endocrine and metabolic functions in the endometrium of PCOS rats."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;319:117346 45. [IF=1.8] Dimeng Song et al."Cryptotanshinone, a Potential SIRT3 Inhibitor, Suppresses Colorectal Cancer Proliferation in vitro and in vivo."Natural Product Communications.;(): 44. [IF=5.195] YiNi Gao et al."Jiedu-Quyu-Ziyin Fang (JQZF) inhibits the proliferation and activation of B cells in MRL/lpr mice via modulating the AKT/mTOR/c-Myc signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;315:116625 43. [IF=6.449] Chaogeng Lyu et al."A field trials-based study reveals the effects of chlormequat chloride on the quality of medicinal plant Salvia miltiorrhiza Bge. (Lamiaceae) in practical cultivation."INDUSTRIAL CROPS AND PRODUCTS.2023 Apr;194:116396 42. [IF=6.208] Huan Zhao et al."Dihydrotanshinone I Inhibits the Lung Metastasis of Breast Cancer by Suppressing Neutrophil Extracellular Traps Formation."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(23):15180 41. [IF=1.496] Wenkai Wu et al."Cryptotanshinone From Salvia miltiorrhiza Inhibits the Growth of Tumors and Enhances the Efficacy of Chemotherapy in a Gastric Cancer Mouse Model."Natural Product Communications 40. [IF=5.988] Keke Guo et al."Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis."Frontiers in Pharmacology.2022; 13: 1036013 39. [IF=0] Danni Wang et al."Identification of Q-Markers from Hedan Tablet by employing “spider-web” mode and taking compounds’ hepatotoxicity into account."Chinese Herbal Medicines.2022 Aug;: 38. [IF=6.317] Ping Huang et al."Optimization of smashing tissue and ultrasonic extraction of tanshinones and their neuroprotective effect on cerebral ischemia/reperfusion injury by inhibiting parthanatos."Food & Function.2022 Aug;: 37. [IF=6.627] Jiadong Hu et al."Identification of Abietane-Type Diterpenoids and Phenolic Acids Biosynthesis Genes in Salvia apiana Jepson Through Full-Length Transcriptomic and Metabolomic Profiling."Frontiers in Plant Science.2022; 13: 919025 36. [IF=7.376] Chengtao Sun et al."Dihydrotanshinone I inhibits ovarian tumor growth by activating oxidative stress through Keap1-mediated Nrf2 ubiquitination degradation."Free Radical Bio Med. 2022 Feb;180:220 35. [IF=6.057] Qi Tong et al.Biosynthesis-based spatial metabolome of Salvia miltiorrhiza Bunge by combining metabolomics approaches with mass spectrometry-imaging.Talanta. 2021 Nov;:123045 34. [IF=2.971] Rubin Cheng et al."Cryptotanshinone enhances the efficacy of Bcr-Abl tyrosine kinase inhibitors via inhibiting STAT3 and eIF4E signalling pathways in chronic myeloid leukaemia."Pharm Biol. 2021;59(1):893-903 33. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 32. [IF=3.411] Liu Hongyan et al."Effect Study of Continuous Monoculture on the Quality of Salvia miltiorrhiza Bge Roots."Biomed Res Int. 2020;2020:4284385 31. [IF=3.51] Li-Ying Peng et al."Salvia miltiorrhiza Restrains Reactive Oxygen Species-Associated Pulmonary Fibrosis via Targeting Nrf2-Nox4 Redox Balance."Am J Chinese Med. 2019 Aug;47(05):1113-1131 30. [IF=3.69] Qian Zhang et al."Qishen Granule alleviates endoplasmic reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia."J Ethnopharmacol. 2020 Apr;252:112573 29. [IF=4.411] Xiaoping Wang et al."Cryptotanshinone Ameliorates Doxorubicin-Induced Cardiotoxicity by Targeting Akt-GSK-3β-mPTP Pathway In Vitro."Molecules. 2021 Jan;26(5):1460 28. [IF=4.411] Yuanyuan Li et al."Quantitative Determination and Validation of Four Ketones in Salvia miltiorrhiza Bunge Using Quantitative Proton Nuclear Magnetic Resonance Spectroscopy."Molecules. 2020 Jan;25(9):2043 27. [IF=5.34] Tao-Fang Cheng et al."Compound Dan Zhi tablet attenuates experimental ischemic stroke via inhibiting platelet activation and thrombus formation."Phytomedicine. 2020 Dec;79:153330 26. [IF=6.475] Shi Qiu et al."Selection of appropriate post-harvest processing methods based on the metabolomics analysis of Salvia miltiorrhiza Bunge."Food Res Int. 2021 Jun;144:110366 25. [IF=7.514] Tong Wang et al."A hydrophobic deep eutectic solvents-based integrated method for efficient and green extraction and recovery of natural products from Rosmarinus officinalis leaves, Ginkgo biloba leaves and Salvia miltiorrhiza roots."Food Chem. 2021 Nov;3 24. [IF=3.361] Taofang Cheng et al."Hybrid multidimensional data acquisition and data processing strategy for comprehensive characterization of known, unknown and isomeric compounds from the compound Dan Zhi Tablet by UPLC-TWIMS-QTOFMS."Rsc Adv. 2019 Mar;9(16):8714-8727 23. [IF=3.414] Yu-xiang Fei et al."Salvia miltiorrhiza Bunge (Danshen) extract attenuates permanent cerebral ischemia through inhibiting platelet activation in rats."J Ethnopharmacol. 2017 Jul;207:57 22. [IF=3.935] Nan Mi et al."Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: An integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis."J Pharmaceut Biomed. 2019 Feb;164:70 21. [IF=5.64] Wu Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466 20. [IF=7.514] Tiehua Zhang et al."In vitro and in silico perspectives on estrogenicity of tanshinones from Salvia miltiorrhiza."Food Chem. 2019 Jan;270:281 19. Xia, Yanqiu, et al. "Cryptotanshinone reverses reproductive disturbances in rats with dehydroepiandrosterone-induced polycystic ovary syndrome." American journal of translational research 9.5 (2017): 2447. 18. 李晓婷,决利利,郝海军,王世广.隐丹参酮纳米混悬剂的制备及其抗肿瘤活性[J].中成药,2021,43(01):6-10. 17. 马丽娟,王锡恩,刘培,陈蜜,张静,彭敏.隐丹参酮调控Wnt/β-catenin信号通路对胃癌细胞抑制作用的研究[J].新中医,2020,52(21):1-5. 16. 陈天朝,耿梦丽,马彦江,李沁,姚超,程思卿,王娇.丹参不同炮制品饮片与标准汤剂的物性参数及化学成分相关性[J].中成药,2021,43(03):824-829 15. 赵志国, 段文娟, 张晓梦,等. HPLC-DAD-ESI-TOF/MS鉴别和测定前列欣胶囊中多种成分及其多指标定量指纹图谱研究[J]. 药物分析杂志, 2017, 037(010):1810-1816. 14. 李清清 张继芬. 冠心宁中14种成分的含量测定[J]. 苏盐科技 2019 046(006):33-35. 13. 王芸, 陈军峰, 张磊,等. 基于"有效成分-性状"的关联分析评价丹参品质的研究[J]. 世界科学技术:中医药现代化, 2019(5):835-843. 12. 崔伟亮. 丹参酒炙前后HPLC指纹图谱色谱峰归属比较[J]. 辽宁中医杂志, v.46;No.507(08):1707-1709. 11. 敏敏 赵志国 刘伟 等. HPLC-DAD法同时测定三种来源丹参饮片中水溶性和脂溶性成分[J]. 山东科学 2019(6). 10. 石蔚华 赵筱萍 陈晓玲.三叶糖脂清DPP-4抑制成分筛选及其调控JNK/AKT信号通路改善胰岛素抵抗的机制研究[J].浙江中医药大学学报 2019 43(01):7-13. 9. 闫妍 石磊 史宁 郭宏举 耿帅 温彬宇.UPLC-Q-TOF-MS同时测定天王补心片中丹参的主要成分[J].解放军药学学报 2018 34(01):55-57. 8. 孙锦 林力 彭勍 等. 不同浓度乙醇提取丹参中12种成分比较研究[J]. 中国中医药信息杂志 2019(9). 7. 郝海军, 屈战果, 范明松. 隐丹参酮纳米结构脂质载体的制备及药动学研究[J]. 中成药, 2020, 042(004):831-835. 6. 邓凤春, 于占江, 杨钰,等. 隐丹参酮对人胃癌细胞SGC-7901凋亡的影响及其机制[J]. 北京中医药大学学报, 2015. 5. 邓凤春, 杨钰, 赵红晔,等. 隐丹参酮抑制人胃癌SGC-7901细胞增殖的实验研究[J]. 中外医疗, 2014(35):49-50. 4. 彭国文,柳超,時晓静,郝海军.隐丹参酮固体脂质纳米粒的制备及药动学研究[J].中药材,2019,42(03):626-629. 3. 何家杰,李敏,唐国富,李厚泽,綦晓龙.异隐丹参酮对胃癌细胞增殖、周期和凋亡的影响[J].临床肿瘤学杂志,2019,24(02):129-132. 2. 张玉, 戚莹雪, 王蕾,等. 山东丹参脂溶性成分的地域分布特点研究[J]. 中药材, 2018, 041(011):2522-2526. 1. 张芮乾,吴晓毅,胡添源,宋雅迪,高伟,黄璐琦.基于丹参酮类化合物生源途径的丹参质量标志物研究思路探讨[J].中国中药杂志,2020,45(13):3098-3103.